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Dr. Hiroshi Kanamori

Gastroenterologist
Superintendent, Tokyo Clinic

  • Present Title & Affiliation

    • Superintendent, Tokyo Clinic

  • Education

    • 1981 M.D.

      School of Medicine, Faculty of Medicine, University of Tokyo

    • 1989 Ph.D.

      Graduate School of Medicine, Kyoto University

  • Certifications

    • Board-certified member of The Japanese Society of Internal Medicine
    • Board-certified Hepatologist and Instructor by The Japan Society of Hepatology
    • Board-certified Gastroenterologist by The Japanese Society of Gastroenterology
    • Board-certified Occupational Physician by Japan Medical Association
    • Industrial Health Consultant

  • Professional Experience

    • 1981

      The University of Tokyo Hospital, Japan

    • 1983

      Tokyo Metropolitan Komagome Hospital, Japan

    • 1984

      The First Dept. of Medical Chemistry, School of Medicine, Kyoto University, Japan

    • 1989

      The Third Dept. of Internal Medicine, School of Medicine, The University of Tokyo, Japan

    • 1990

      National Institute of Health and Nutrition, Japan

    • 1992

      The Third Dept. of Internal Medicine, School of Medicine, The University of Tokyo, Japan

    • 1993

      Visiting Research Associate, Dept of Biochemistry, University of Illinois at Urbana–Champaign, USA
      Visiting Professor, Dept. of Internal Medicine, College of Medicine, University of Illinois at Urbana–Champaign, USA

    • 1998

      Dept. of Gastroenterology, The University of Tokyo Hospital, Japan

    • 2012

      Medical Director, Clinic of Japan Bank for International Cooperation and Development Bank of Japan, Japan
      Corporate Physician, Development Bank of Japan, Japan

    • 2022-present

      Superintendent, Tokyo Clinic, Japan

  • Skill Highlights

    • Gastroenterology
    • Hepatology

  • Professional Memberships

    • 1984-present

      The Japan Society of Hepatology

    • 1990-present

      The Japanese Society of Internal Medicine

    • 1992-present

      The Japanese Society of Gastroenterology

    • 2022-present

      Japan Society of Ningen Dock

  • Honor & Awards

    • 1985

      Research Grant Award, Sankyo Foundation of Life Science

    • 1991

      Research Grant Award, The Cell Science Research Foundation

    • 1993

      Research Grant Award, Japan Research Foundation for Clinical Pharmacology

  • Selected Publications

    • Kanamori H, Suzuki N, Siomi H, Nosaka T, Sato A, Sabe H, Hatanaka M, Honjo T. HTLV-1 p27rex stabilizes human interleukin-2 receptor alpha chain mRNA. EMBO J 1990;9(12):4161-4166.
    • Matsumoto A, Naito M, Itakura H, Ikemoto S, Asaoka H, Hayakawa I, Kanamori H, Aburatani H, Takaku F, Suzuki H, Kobari Y, Miyai T, Takahashi K, Cohen EH, Wydro R, Housman DE, Kodama T.  Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions. Proc Natl Acad Sci U S A 1990;87(23):9133-9137.
    • Kanamori H, Dodson RE, Shapiro DJ. In vitro genetic analysis of the RNA binding site of vigilin, a multi- KH-domain protein. Mol Cell Biol 1998; 18(7):3991-4003.
    • Kanamori H, Krieg S, Mao C, Di Pippo VA, Wang S, Zajchowski DA, Shapiro DJ. Proteinase inhibitor 9, an inhibitor of granzyme B-mediated apoptosis, is a primary estrogen-inducible gene in human liver cells. J Biol Chem. 2000;275(8): 5867-5873.
    • Huang Y, Uchiyama Y, Fujimura T, Kanamori H, Doi T, Takamizawa A, Hamakubo T, Kodama T. A human hepatoma cell line expressing hepatitis c virus nonstructural proteins tightly regulated by tetracycline. Biochem Biophys Res Commun. 2001; 281(3): 732-740.
    • Matsuhashi N, Watanabe K, Kanamori H, Ohnishi S, Omata M. PPARgamma agonists for intestinal ischaemia. Lancet. 2001; 358(9275): 75-76.
    • Uchiyama Y, Huang Y, Kanamori H, Uchida M, Doi T, Takamizawa A, Hamakubo T, Kodama T. Measurement of HCV RdRp activity with C-terminal 21 aa truncated NS5b protein: optimization of assay conditions. Hepatol Res. 2002; 23(2): 90-97.
    • Gunji T, Kawauchi N, Akahane M, Watanabe K, Kanamori H, Ohnishi S. Long-term outcomes of transcatheter arterial chemoembolization with autologous blood clot for unresectable hepatocellular carcinoma. Int J Oncol. 2002; 21(2): 427-432
    • Gunji T, Kawauchi N, Akahane M, Watanabe K, Kanamori H, Ohnishi S. Treatment of unresectable hepatocellular carcinoma less than 2 centimeters by transcatheter arterial chemoembolization with autologous blood clot. J Clin Gastroenterol. 2003; 36(4): 347-351
    • Kanamori H, Yuhashi K, Uchiyama Y, Kodama T, Ohnishi S. In vitro selection of RNA aptamers that bind the RNA-dependent RNA polymerase of hepatitis C virus: a possible role of GC-rich RNA motifs in NS5B binding. Virology. 2009; 388: 91-102
    • Kanamori H, Yuhashi K, Ohnishi S, Koike K, Kodama T. RNA-dependent RNA polymerase of hepatitis C virus binds to its coding region RNA stem-loop structure, 5BSL3.2, and its negative strand. J Gen Virol. 2010; 91: 1207-1212.
    • Yuhashi K, Ohnishi S, Kodama T, Koike K, Kanamori H. In vitro selection of the 3'-untranslated regions of the human liver mRNA that bind to the HCV nonstructural protein 5B. Virology. 2014 450-451:13-23
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