Ichiro Seto, M.D., D.M.D., D.D.Sc., Ph.D.
Oral and Maxillofacial Surgeon / Regenerative Medicine Doctor / Associate Specialist, Southern TOHOKU Proton Beam Therapy Center
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Present Title & Affiliation
- Associate Specialist, Southern TOHOKU Proton Beam Therapy Center
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Education
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1996 B.D.Sc.
Faculty of Denstisry, Tokyo Medical and Dental University, Japan
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1996 D.M.D.
Registered Dentist, Ministy of Health, Welfare and Labour, Japan
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2000 D.D.Sc.
Graduate School of Medicine and Dental Sciences, Tokyo Medical and Dental University, Japan
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2009 M.B.B.S.
Faculty of Medicine, University of Bern, Switzerland
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2009 M.D.
Registerd Doctor, Federal Office of Public Health (FOPH), Switzerland
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2010 Ph.D.
Faculty of Medicine, University of Bern, Switzerland
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2014 M.D.
Registered Doctor, Ministy of Health, Welfare and Labour, Japan
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Certifications
- Board-certified Oral and Maxillofacial Surgeon by Japanese Society for Oral and Maxillofacial Surgeons (JSOMS)
- Board-certified Regerenrative Medicine Doctor by The Japanese Society for Regenerative Medicine (JSRM)
- Board-certified Oral
and Maxillofacial Surgery instructor by Ministy of Health, Welfare and Labour, Japan
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Professional Experience
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1996-1997
Junior Resident, Toyko Medical and Dental University Dental Hospital, Japan
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2000-2002
Clinical Fellow, Dept. of Oral and Maxillofacial Surgery, Toyko Medical and Dental University Dental Hospital, Japan
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2002-2003
Senior Resident, Dept. of Anesthesiology, Surgical Operation Management Unit, Chiba Cancer Center, Japan
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2009-2010
Clinial Fellow, Dept. of Cranio-Maxillofacial Surgery, Inselspital, Bern University Hospital, Switzerland
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2010
Lecturer, Dept. of Oral-Maxillofacial Surgery and Orthodontics, The University of Tokyo Hospital, Japan
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2010-2014
Senior Lecturer, Dept. of Oral-Maxillofacial Surgery and Orthodontics, The University of Tokyo Hospital, Japan
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2014-2015
Director, Dept. of Oral and Maxillofacial Surgery, Southern TOHOKU General Hospital, Japan
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2014-2015
Deputy Chair, Division of International Healthcare services, Southern TOHOKU General Hospital, Japan
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2015-2017
Resident, Southern TOHOKU General Hospital, Japan
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2017-2018
Clinical Fellow, Southern TOHOKU Proton Beam Therapy Center, Japan
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2018-present
Associate Specialist, Southern TOHOKU Proton Beam Therapy Center, Japan
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Skill Highlights
- Radiotherapy
- Dentoalveolar surgery
- Oral and maxillofacial surgery
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Professional Memberships
- Japan Radiological Society (JRS)
- Japanese Society for Radiation Oncology (JASTRO)
- Japan Society of Head and Neck Cacner (JSHNC)
- Japanese Society for Oral and
Maxillofacial Surgeons (JSOMS)
- The Japanese Society for Regenerative Medicine (JSRM)
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Honors & Awards
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2000
Invetigator Award, Tokyo Medical and Dental University (TMDU), Japan
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Selected Publications
Scientific Papers
- Seto I, Toda H, Moriyama T, Nakajima Y, Ishii Y, Enomoto S. A case of congenital insensitivity to pain with anhydrosis associated wit unusual healing buccal ulcer.2000, Jap J Oral Maxilllofac Surg (48, 602-604)
- Seto I, Asahina I, Oda M, Enomoto S. Reconstruction of the primate mandible
with a combination graft of recombinant human bone morphogenetic protein-2 and
bone marrow. 2001, J Oral Maxillofac Surg. (59, 53-61)
- Marukawa E, Asahina I, Oda M, Seto I, Alam MI, Enomoto S. Bone
regeneration using recombinant human bone morphogenetic protein-2 (rhBMP-2) in
alveolar defects of primate mandibles. 2001 Br J Oral Maxillofac Surg. (39,
452-459)
- Alam MI, Asahina I, Seto I, Oda M, Enomoto S. Prefabricated
vascularized bone flap: a tissue transformation technique for bone
reconstruction. 2001, Plast Reconstr Surg (108, 952-958)
- Seto I, Tachikawa N, Mori M, Hoshino S, Marukawa E, Asahina I, Enomoto S.
Restoration of occlusal function using osseointegrated implants in the canine
mandible reconstructed by rhBMP-2. 2002 Clin Oral Implants Res (13,536-541)
- Asahina I, Marukawa E, Seto I. Bone Morphogenetic Protein; BMP
and Bone Regeneration. 2002, Clinical Calcium (12, 44-49)
- Asahina I, Marukawa E, Seto
I. Bone regeneration using bone morphogenetic protein (BMP). 2002
Clin Calcium (12,222-227)
- Abe M, Yoda T, Imai H, Sakamoto I, Seto I, Omura K. Lateral Disc displacement of
temporomandibular joint treated by arthrocentesis and lavage. 2002 J Jap Soc
for Temporomandibular Joint (14(1), 46-50)
- Marukawa E, Asahina I, Oda M, Seto I, Alam M, Enomoto S.
Functional reconstruction of the non-human primate mandible using recombinant
human bone morphogenetic protein-2. 2002, Int J Oral Maxillofac Surg
(31:287-295)
- Nakajima Y, Seto I, Maruoka Y, Omura K. A case of lymphoepithelial
cyst of parotid gland. 2003, Jap J Oral Maxilllofac Surg (49,408-410)
- Alam MI, Asahina I, Seto I, Oda M, Enomoto S. Prefabrication of
vascularized bone flap induced by recombinant human bone morphogenetic protein
2 (rhBMP-2). 2003, Int J Oral Maxillofac Surg (32, 508-514)
- Seto I, Omura K, Harada H, Harashima M, Abe M, Okada N. A case of
polymorphous low-grade adenocarcinoma of the palate.2003, Jap J Oral
Maxilllofac Surg (49, 446-449)
- Iizuka T, Häfliger J, Seto I, Rahal A, Mericske-Stern R, Smolka
K. Oral rehabilitation after mandibular reconstruction using an osteocutaneous
fibula free flap with endosseous implants: Factors affecting the functional
outcome in patients with oral cancer. 2005, Clin Oral Impl Res (16,69-79)
- Büchel P, Rahal A, Seto I, Iizuka T. Reconstruction of orbital
floor fracture with Polyglactin 910/Polydioxanon patch (Ethisorb®): A
retrospective study. 2005, J Oral Maxillofac Surg (63, 646-650)
- Seto I, Marukawa E, Asahina I. Mandibular reconstruction using a combination
graft of rhBMP-2 with Bone marrow cells expanded in vitro. 2006, Plast Reconstr
Surg, (March 117(3), 902-903)
- Iizuka T, Hallermann W, Seto I, Smolka W. – Technical note - A
titanium arch bar for maxillomandibular fixation in oral and maxillofacial surgery.
2006 J Oral Maxillofac Surg, (64(6), 989-992)
- Iizuka T, Eggensperger N, Wilke S, Seto I, Thüer U. An
alternative soft tissue analysis following mandibular setback by sagittal split
ramus osteotomy. 2005, Oral Surg Oral Med Oral Path Oral Radiol Endod (100,
E1-8)
- Iizuka T, Hallermann W, Seto I, Smolka W, Smolka K, Bosshardt DD.
Bi-directional distraction osteogenesis of the alveolar bone using an
extraosseous device. 2005, Clin Oral Impl Res, (Dec, 16(6), 700-707)
- Suenaga H, Saijo H, Chikazu D, Fujihara H, Sugiyama M, Ohkubo K, Seto
I, Mori Y, Iino M, Takato T. A case
of necrotizing ulcerative stomatitis in a neutropenic patient with malignant
lymphoma. 2008, Asian J. Oral. Maxillofac. Surg. (No.4, Vol. 20)
- Iino M, Fukuda M, Nagai H, Hamada Y, Yamada H, Nakaoka K, Mori Y,
Chikazu D, Saijo H, Seto I, Ohkubo K, Takato T. Evaluation of 15
mandibular reconstructions with Dumbach Titan Mesh System and particulate
cancellous bone and marrow harvested from bilateral posterior ilia. 2009, Oral
Surg Oral Med Oral Path Oral Radiol Endod, (107 (4) ,E1-8)
- Chikazu D, Taguchi T, Koyama H, Hikiji H, Suenaga H, Saijo H, Mori Y, Seto
I, Iino M, Takato T. Improvement in Wound Healing by a Novel Synthetic
Collagen-gel Dressing in Genetically Diabetic Mice. 2010, Asian J Oral
Maxillofac Surg. Vol. 22 issue 2 August, 61-67
- Gutwald R, Haberstroh J, Stricker A, Rüther E, Otto F, Xavier SP, Oshima
T, Marukawa E, Seto I, Enomoto S, Hoogendijk CF, Schmelzeisen R,
Sauerbier S: Influence of rhBMP-2 on bone formation and osseointegration in
different implant systems after sinus-floor elevation. An in vivo study on
sheep. J Craniomaxillofac Surg. 2010 Dec;38(8):571-9.
- Broggini N, Hofstetter W, Hunziker E, Bosshardt DD, Bornstein MM, Seto
I, Weibrich G, Buser D: The Influence of PRP on Early Bone Formation in
Membrane Protected Defects. A Histological and Histomorphometric Study in
theRabbit Calvaria. Clin Implant Dent Relat Res.2010 13(1): 1-12
- Thoren H, Seto I, Buettner M, Shaller B, Suominen AL, Iizuka T.
Patterns of frontobasal and frontobasal fractures in children and teenagers
relative to developmental stage of the facial skelton. Arch Otolaryngok Head
Neck Surg. 2011 Jun; 137(6):549-556.
- Saijo H, Koga Y, Mori Y, Seto I, Abe M, Ohkubo K, Hoshi K, Takato
T. Application of oercutaneous arch osteotomy for protrusion deformity of the
zygoma following facial surgery. J Oral Maxillofac Surg. 2014, 26: 138-141
- Takayama K, Kato T, Nakamura T, Azami Y, Ono T, Suzuki M, Takada A,
Yamaguchi H, Seto I, Nakasato T, Wada H, Kikuchi Y, Mitsudo K, Fuwa N,
Murakami M. Proton Beam Therapy Combined with Intra-Arterial Infusion
Chemotherapy for Stage IV 25.Adenoid Cystic Carcinoma of the Base of the
Tongue. Cancers 2018 Sept22, 11(10)
- Hiromasa Endo, Kanako Takayama, Kenji Mitsudo, Tatsuya Nakamura, Ichiro
Seto, Hisashi Yamaguchi, Takashi Ono, Motohisa Suzuki, Yusuke Azami,Hitoshi
Wada, Masao Murakami, Iwai Tohnai, Proton beam therapy in combination with
intra-arterial infusion chemotherapy for T4 squamous cell carcinoma of the
maxillary gingiva. Cancers 2018 Sept15, 10(9)
- Mao Nishikawa, Michitaka Honda, Ryosuke Kimura, Ayaka Kobayashi, Yuji
Yamaguchi, Hiroshi Kobayashi, Hidetaka Kawamura, Yujiro Nakayama, Yukitoshi
Todate, Yoshinao Takano, Hisashi Yamaguchi, Koichi Hamada, Susumu Iketani, Ichiro
Seto, Kanichi Seto.Clinical impact of periodontal disease on postoperative
complications in gastrointestinal cancer patients.Int J Clin Oncol 2019 Dec; 24(12):1558-1564.
- Mao Nishikawa, Michitaka Honda, Ryosuke Kimura, Ayaka Kobayashi, Yuji
Yamaguchi, Hiroshi Kobayashi, Hidetaka Kawamura, Yujiro Nakayama, Yukitoshi
Todate, Yoshinao Takano, Hisashi Yamaguchi, Koichi Hamada, Susumu Iketani, Ichiro
Seto, Kanichi SetoBacteriological examination of stomach mucosa and
periodontal pocket in patients with gastric cancer: A study protocol. Ann.
Cancer Res. Ther. 2019 Vol. 27 No.1 pp. 1-3
- Y Shimazu, R Otsuki, M Murakami, A konishi, K Kan, I Seto, H Yamaguchi,
T Hattori. : Age as a decisive factor in general anesthesia use in pediatric
proton beam therapy Nature scientific reports in press 2021.
- Katsumi Hirose, Akiyoshi Konno, Junichi Hiratsuka, Seiichi Yoshimoto,
Takahiro Kato, Koji Ono, Naoki Otsuki, Jun Hatazawa, Hiroki Tanaka, Kanako
Takayama, Hitoshi Wada, Motohisa Suzuki, Mariko Sato, Hisashi Yamaguchi, Ichiro
Seto, Yuji Ueki, Susumu Iketani, Shigeki Imai, Tatsuya Nakamura, Takashi
Ono, Hiromasa Endo, Yusuke Azami, Yasuhiro Kikuchi, Masao Murakami, Yoshihiro
Takai. : Boron Neutron Capture Therapy Using Cyclotron-Based Epithermal Neutron
Source and Borofalan(10B) for Recurrent or Locally Advanced Head and Neck
Cancer (JHN002): An Open-Label Phase II Trial in submission.
Authorship in Books
- Asahina I, Seto I, Oda M, Marukawa E, Imranul AM, Enomoto S. Regeneration of Bone Tissue and restoration of occlusional function using rhBMP-2. (Chapter 49 in Bone Engineering). Ed. Davies, 2000, 526-532.
- Iizuka T, Seto I: A clinical experience with a new
two-directional distraction system for the alveolar ridge. 2005, 14-21. Oral
Surgery Handmanual YEARBOOK, 2005. The
Quintessense. (Published
in Japanese)
- Seto I, Yanai C, Iizuka T. Clinical Application of alveolar distraction with
special emphasis on complication. 2006, 104-110. Oral Surgery Handmanual
YEARBOOK, 2006. The Quintessense. (Published in Japanese)
- Seto I, Lieger O, Smolka K, Iizuka T. Operative Indication for Orbita floor
fracture. 2007, 230-235. Oral Surgery Handmanual YEARBOOK, 2007. The Quintessense.
(Published in
Japanese)
- Seto I, Iizuka T. The type of Osteosynthese system and indication in the
maxillofacial area.2010, 203-210. Oral Surgery Handmanual YEARBOOK, 2010. The Quintessense. (Published in Japanese)
- Seto I, Hosokawa S, Iizuka T. Fracture classification and basic reduction
technique in craniomaxillofacial area. 2011, 175-181. Oral Surgery Handmanual
YEARBOOK, 2011. The Quintessense. (Published in Japanese)
- Seto I, Saijo H. Chapter 2, Mandibular Fracture. Treatment and medicine guidebook.
2013,78-79. The Quintessense. (Published in Japanese)
- Seto I et.al as a Editor. Nursing Dictionary. 6th Ed. 2012, Medical friend Co,
Tokyo. (Published
in Japanese)
- Seto I, Saijo H. Minor Emergency in Oral surgery area. Chapter 4. Temporpmandibular
Joint Luxation. 2014 Monthly Medical Practice.
(Published in Japanese)
- Seto I, Shimozato K, R J Radlanski, K H Wesker. FACE (Das Gesicht Bildatlas
klinische Anatomie).,2014. The Quintessense. (Published in Japanese)