Takayama.jpg

Kanako Takayama, M.Sc., D.M.D., Ph.D.

Oral-Maxillofacial Radiation Oncologist
Associate Specialist,Southern TOHOKU Proton Beam Therapy Center

  • Present Title & Affiliation

    • Associate Specialist, Southern TOHOKU Proton Beam Therapy Center

  • Education

    • 1999 B.Sc. in Health Sciences 

      School of Integrated Health Sciences, Faculty of Medicine, The University of Tokyo, Japan

    • 2001 M.Sc. in Health Sciences

      Gradaute School of Medicine, The University of Tokyo, Japan

    • 2008 B.D.Sc.

      Faculty of Dentistry, Tokyo Medical and Dental University, Japan

    • 2008 D.M.D.

      Registered Dentist, Ministy of Health, Welfare and Labour, Japan

    • 2016 Ph.D.

      Yokohama City University Graduate School of Medicial Science, Japan

  • Certifications

    • 2012

      Board-certified Dental Radiologist by Japanese Society for Oral and Maxillofacial Radiology (JSOMFR)

    • 2014

      Board-qualified Oral-Maxillofacial Radiation Oncologist by Japanese Society for Oral and Maxillofacial Radiology (JSOMFR)

    • 2016

      Board-certified Oral and Maxillofacial Surgeon by Japanese Society of Oral and Maxillolofacial Surgeons (JSOMS)

  • Professional Experience

    • Apr. 2008

      Junior Dental Resident, Dental Hospital, Tokyo Medical and Dental University, Japan

    • Oct. 2008-Mar. 2009

      Dental Resident, Sothern TOHOKU General Hospital and Clinic, Japan

    • 2009-2014

      Clinical Fellow, Southern TOHOKU Proton Beam Therapy Center, Japan

    • 2014-2016

      Clinical Instructor, Dept. of Oral and Maxillofacial Surgery, Yokohama City Univeristy Hospital, Japan

    • 2014-2016

      Ph.D. candidate, Yokohama City University Graduate School of Medicial Science, Japan

    • 2016-present

      Associate Specialist, Southern TOHOKU Proton Beam Therapy Center, Japan

  • Skill Highlights

    • Chemo-radiotherapy for head and neck canncers

  • Professional Memberships

    • Japanese Society for Radiation Oncology (JASTRO)
    • Japan Society for Head and Neck Cacner (JSHNC)
    • Japanese Society of Oral Oncology (JSOO)
    • Japanese Society for Oral and Maxillofacial Radiology (JSOMFR)
    • Japanese Society of Oral and Maxillolofacial Surgeons (JSOMS)
    • Japan Society of Medical Physics (JSMP)

  • Honors & Awards

    • 2010

      Best Poster Award, the 49th Annual Meeting of the Particle Therapy Cooperative Group (PTCOG 49), Gunnma, Japan

    • 2020

      Best Poster Award, the 38th Anual Meeting of Japanese Society of Oral Oncology, Tokyo, Japan
      Title: Combination threapy of Proton Beam Treatment with Retrograde Superselective Intra-arterial Chemoradiotherapy for Advanced Oral Cancer: A study on the cases including oral cancer associated with cervical lymph node metastasis.

  • Selected Publications

    • Takayama K, Nakamura T, Takada A, Kato T, Sakuma H, Mitsudo K, Fuwa N, Murakami M. Proton beam therapy combined with retrograde intra-arterial infusion chemotherapy for an extremely rapid growing recurrent ameloblastic carcinoma: a case report. Mol. and clin. Oncol. 2020, 13(4). DOI: 10.3892/mco.2020.2104
    • Yamaguchi H, Honda M, Hamada K, Kobayashi H, Todate Y, Seto I, Takayama K, Suzuki M, Wada H, Kikuchi Y, Murakami M. The effectiveness of proton beam therapy for liver metastatic recurrence in gastric cancer patients. Jpn J Clin Oncol. 2020 May 4:hyaa052. doi: 10.1093/jjco/hyaa052. Online ahead of print.PMID: 32363379
    • Takayama K, Kato T, Nakamura T, Azami Y, Ono T, Suzuki M, Takada A, Yamaguchi H, Seto I, Nakasato T, Wada H, Kikuchi Y, Mitsudo K, Fuwa N, Murakami M: Proton Beam Therapy Combined with Intra-Arterial Infusion Chemotherapy for Stage IV Adenoid Cystic Carcinoma of the Base of the Tongue. Cancers (Basel), 11(10):1413, 2019.
    • Azami Y, Hayashi Y, Nakamura T, Kimura K, Yamaguchi H, Ono T, Takayama K, Hirose K, Yabuuchi T, Suzuki M, Hatayama Y, Hareyama M, Kikuchi Y, Fuwa N. Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer. Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):49-54. doi: 10.1007/s12070-016-1008-y. Epub 2016 Jul 9. PMID: 31741929
    • Endo H, Takayama K, Mitsudo K, Nakamura T, Seto I, Yamaguchi H, Ono T, Suzuki M, Azami Y, Wada H, Murakami M, Tohnai I. Proton Beam Therapy in Combination with Intra-Arterial Infusion Chemotherapy for T4 Squamous Cell Carcinoma of the Maxillary Gingiva. Cancers (Basel). 2018;10(9). pii: E333. doi: 10.3390/cancers10090333.
    • Ono T, Nakamura T, Yamaguchi H, Azami Y, Takayama K, Suzuki M, Wada H, Kikuchi Y, Murakami M, Nemoto K, Clinical results of proton beam therapy for elderly patients with non-small cell lung cancer. Radiat Oncol. FEB., 2018; 13: 19.
    • Kimura K, Nakamura T, Ono T, Azami Y, Suzuki M, Wada H, Takayama K, Endo H, Takeyama T, Hirose K, Takai Y, Kikuchi Y. Clinical results of proton beam therapy for hepatocellular carcinoma over 5 cm. Hepatol Res. 2017 Dec;47(13):1368-1374. doi: 10.1111/hepr.12874. Epub 2017 Mar 29. PMID: 28198132
    • Yuichiro Hayashi, Tatsuya Nakamura, Kenji Mitsudo, Kanako Kimura, Hisashi Yamaguchi, Takashi Ono, Yusuke Azami, Kanako Takayama, Katsumi Hirose, Tomonori Yabuuchi, Motohisa Suzuki, Yoshiomi Hatayama, Yasuhiro Kikuchi, Hitoshi Wada, Nobukazu Fuwa, Masato Hareyama, Iwai Tohnai, Re-irradiation using proton beam therapy combined with weekly intra-arterial chemotherapy for recurrent oral cancer, ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY 2017 Oct;13(5):e394-e401.
    • Yuichiro Hayashi, Tatsuya Nakamura, Kenji Mitsudo, Hisashi Yamaguchi, Takashi Ono, Yusuke Azami, Kanako　Takayama, Motohisa Suzuki, Yoshiomi Hatayama, Iwao Tsukiyama, Masato Hareyama, Yasuhiro Kikuchi, Nobukazu Fuwa, Iwai Tohnai, Retrograde intra-arterial chemotherapy and daily concurrent proton beam therapy for recurrent oral cavity squamous cell carcinoma: Analysis of therapeutic results in 46 cases, HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 38(8) 1145 - 1151
    • Akinori Takada, Tatsuya Nakamura, Kanako Takayama, Chiyoko Makita, Motohisa Suzuki, Yusuke Azami, Takahiro Kato, Iwao Tsukiyama, Masato Hareyama, Yasuhiro Kikuchi, Takashi Daimon, Yutaka Toyomasu, Noriko Ii, Yoshihito Nomoto, Hajime Sakuma, Nobukazu Fuwa, Preliminary treatment results of proton beam therapy with chemoradiotherapy for stage I-III esophageal cancer, Cancer medicine 2016, 5(3) 506 - 515
    • Kanako Takayama, Tatsuya Nakamura, Akinori Takada, Chiyoko Makita, Motohisa Suzuki, Yusuke Azami, Takahiro Kato, Yuichiro Hayashi, Takashi Ono, Yutaka Toyomasu, Masato Hareyama, Yasuhiro Kikuchi, Takashi Daimon, Kenji Mitsudo, Iwai Tohnai, Nobukazu Fuwa, Treatment results of alternating chemoradiotherapy followed by proton beam therapy boost combined with intra-arterial infusion chemotherapy for stage III-IVB tongue cancer, Journal of Cancer Research and Clinical Oncology, 2016, 142(3) 659 - 667
    • Tatsuya Nakamura, Yusuke Azami, Takashi Ono, Hisashi Yamaguchi, Yuichiro Hayashi, Motohisa Suzuki, Yoshiomi Hatayama, Iwao Tsukiyama, Masato Hareyama, Yasuhiro Kikuchi, Kanako Takayama, Nobukazu Fuwa, Preliminary results of proton beam therapy combined with weekly cisplatin intra-arterial infusion via a superficial temporal artery for treatment of maxillary sinus carcinoma, JAPANESE JOURNAL OF CLINICAL ONCOLOGY, 2016, 46(1) 46 - 50
    • Chiyoko Makita, Tatsuya Nakamura, Akinori Takada, Kanako Takayama, Motohisa Suzuki, Yusuke Azami, Takahiro Kato, Iwao Tsukiyama, Masato Hareyama, Yasuhiro Kikuchi, Takashi Daimon, Masaharu Hata, Tomio Inoue, Nobukazu Fuwa, High-dose proton beam therapy for stage I non-small cell lung cancer: Clinical outcomes and prognostic factors. Acta oncologica (Stockholm, Sweden), 2015, 54(3) 307 - 14
    • Kanako Takayama, Yusuke Demizu, Nobukazu Fuwa, Chapter 11; Radiotherapy, In Book “Oral Cancer” Published by Springer Japan (Ed. By T. Kirita and K. Omura), 2015
    • Makita C, Nakamura T, Takada A, Takayama K, Suzuki M, Ishikawa Y, Azami Y, Kato T, Tsukiyama I, Kikuchi Y, Hareyama M, Murakami M, Fuwa N, Hata M, Inoue T, Clinical outcomes and toxicity of proton beam therapy for advanced cholangiocarcinoma, Radiat Oncol. 2014, 14(9) 26
    • Makita C, Nakamura T, Takayama K, Takada A, Fuwa N, Sakuma H, Proton beam therapy and continuous intra-arterial chemotherapy for polymorphous low-grade adenocarcinoma in the hard palate. 2013, Case Rep Oncol. 6(1) 66 - 71
    • Tatsuya Nakamura, Nobukazu Fuwa, Kanako Takayama, Haruo Inokuchi, Takuya Tomoda, Akinori Takada, Chiyoko Makita, Miho Shiomi, Jun-ichi Yokouchi, Kazuo Watanabe, Phase I study of weekly docetaxel and cisplatin arterial infusion for recurrent head and neck cancer, HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2012, 34(11) 1634 - 1639
    • Tatsuya Nakamura, Nobukazu Fuwa, Kanako Takayama, Takuya Tomoda, Akinori Takada, Chiyoko Makita, Miho Shiomi, Jun-ichi Yokouchi, Kazuo Watanabe, A new method using MRI to delineate areas of head and neck cancer targeted by intra-arterial infusion via a superficial temporal artery, ORAL ONCOLOGY 2011, 47(5) 387 - 390
    • Noriyuki Kadoya, Yasunori Obata, Takahiro Kato, Masaru Kagiya, Tatsuya Nakamura, Takuya Tomoda, Akinori Takada, Kanako Takayama, Nobukazu Fuwa, Done-volume comparision of proton radiotherapy and stereotactic body resiotherapy for non-small-cell lung cancer, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2011, 79(4) 1225 - 1231
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